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Molecular Reproduction & Development Volume 83, Issue 8, August 2016
Publication year - 2016
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.22560
Subject(s) - biology , niche , microbiology and biotechnology , stem cell , drosophila (subgenus) , microtubule , tubulin , cell cortex , stem cell niche , germ cell , cell , genetics , cytoskeleton , ecology , gene , progenitor cell
Drosophila male germ‐line stem cells possess microtubule‐based nanotubes (MT‐nanotubes), unique cellular protrusions observed specifically within stem cell populations. These MT‐nanotubes promote Decapentaplegic (Dpp) signal reception, which contributes to the short‐range nature of niche‐stem cell signaling (see Inaba et al., this issue). This image shows a three‐dimensional reconstruction of a testicular niche, illustrating how MT nanotubes (GFP‐alpha‐tubulin; green) penetrate into neighboring niche cells (Hub cell cortex, Armadillo staining; red) .