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Molecular Reproduction & Development Volume 81, Issue 9, September 2014 cover image
Publication year - 2014
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.22249
Subject(s) - biology , atp binding cassette transporter , mcherry , transporter , microbiology and biotechnology , embryo , abcc1 , multidrug resistance associated proteins , green fluorescent protein , genetics , gene
ATP‐binding cassette (ABC) transporters are important for embryonic development. In this issue, Gokirmak et al. review insights and methods to study multidrug resistance (MDR)‐type ABC transporters in sea urchin embryos. This montage shows embryos expressing various MDR transporters—including ABCB1, ABCC1, ABCC9, and ABCG2, tagged with GFP, YFP, mCherry, and CFP, respectively—to identify where they reside. ABCC9, for example, localizes to large apical vesicles. A Leica SP8 confocal microscope was used to capture these images.