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Molecular Reproduction & Development Volume 81, Issue 8, August 2014 cover image
Publication year - 2014
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.22247
Subject(s) - biology , sumo protein , bub1 , centromere , metaphase , spindle checkpoint , microbiology and biotechnology , ubiquitin , protein kinase a , kinase , genetics , chromosome segregation , kinetochore , chromosome , gene
Sumoylation is a modification that can be made to many kinds of proteins and is involved in many biological functions. Bub1‐related kinase (BubR1) is a spindle assembly checkpoint protein that can be modified by small ubiquitin‐related modifier‐1 (SUMO‐1). Yuan at el. (this issue) found that centromere localization of BubR1 (green) in metaphase‐I‐stage oocytes was altered after inhibition of SUMO‐1.