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Molecular Reproduction & Development Volume 80, Issue 5, May 2013 cover image
Publication year - 2013
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.22090
Subject(s) - sertoli cell , cytoskeleton , biology , actin , microbiology and biotechnology , regulator , blood–testis barrier , actin cytoskeleton , endocrinology , medicine , spermatogenesis , cell , genetics , gene
The actin cytoskeleton is an integral part of specialized structures in Sertoli cells of the postpubertal mammalian testis, contributing to the blood testis barrier and the apical ectoplasmic specialization. In a study by Niedenberger et al. (this issue), a dominant regulator of the actin cytoskeleton, Palladin, unexpectedly moves into Sertoli cell nuclei as these cytoskeletal structures form at puberty. This image is a cross‐section of an adult stage‐VIII tubule stained for Palladin (brown) and counterstained with hematoxylin (blue).