Premium
Behavior of sperm nuclei incorporated into parthenogenetic mouse eggs prior to the first cleavage division
Author(s) -
Maleszewski Marek
Publication year - 1992
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.1080330215
Subject(s) - pronucleus , biology , mitosis , blastomere , interphase , cell division , sperm , cytoplasm , microbiology and biotechnology , metaphase , cleavage (geology) , embryo , genetics , cell , zygote , chromosome , embryogenesis , gene , paleontology , fracture (geology)
When artificially activated mouse eggs are inseminated in the middle of the first cell cycle, sperm nuclei remain condensed until the first mitosis. During mitosis of the first cleavage division sperm nuclei decondense, subsequently recondense and are passively displaced to the daughter blastomeres. In the 2‐cell embryos sperm nuclei form interphase nuclei which are able to replicate DNA and to condense into discrete chromosomes during the following mitotic division. These observations suggest that the mitotic cytoplasm of 1‐cell embryos creates similar conditions for the transformation of sperm nuclei into male pronuclei as the cytoplasm of metaphase ll oocytes. © 1992 Wiley‐Liss, Inc.