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Developmental appearance of proteins identified by two‐dimensional gel electrophoresis in mouse gonadal tissue
Author(s) -
Durbin E. J.,
Erickson R. P.,
van Keuren M. L.,
Iacob R. A.,
Kurnit D. M.
Publication year - 1991
Publication title -
molecular reproduction and development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 105
eISSN - 1098-2795
pISSN - 1040-452X
DOI - 10.1002/mrd.1080280305
Subject(s) - biology , ovary , development of the gonads , gel electrophoresis , sexual differentiation , sexual dimorphism , fetus , two dimensional gel electrophoresis , endocrinology , andrology , gonad , genetics , proteomics , gene , pregnancy , medicine
Gonadal protein patterns of the mouse were studied during fetal development by two‐dimensional gel electrophoresis. Fetal mice at days 8.5, 10.5, 12.5, and 14.5 post‐coitum were analyzed for male or female specific proteins. Although no sex specific proteins were found, several proteins were found which were expressed in significantly different amounts in the two sexes at about the time of gonadal differentiation. Hence, quantitative differences, rather than qualitative ones, could be related to the initiation of testis or ovary development.