Comparison of intracytoplasmic sperm injection for inbred and hybrid mice | Zendy

Kawase Yosuke | Zendy; Iwata Takamitsu | Zendy; Toyoda Yutaka | Zendy; Wakayama Teruhiko | Zendy; Yanagimachi Ryuzo | Zendy; Suzuki Hiroshi | Zendy

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Comparison of intracytoplasmic sperm injection for inbred and hybrid mice

Author(s) -

Kawase Yosuke,

Iwata Takamitsu,

Toyoda Yutaka,

Wakayama Teruhiko,

Yanagimachi Ryuzo,

Suzuki Hiroshi

Publication year - 2001

Publication title -

molecular reproduction and development

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.745

H-Index - 105

eISSN - 1098-2795

pISSN - 1040-452X

DOI - 10.1002/mrd.1063

Subject(s) - intracytoplasmic sperm injection , biology , embryo , human fertilization , oocyte , andrology , inbred strain , sperm , embryogenesis , c57bl/6 , oocyte activation , genetics , in vitro fertilisation , immunology , gene , medicine

We compared the results of intracytoplasmic sperm injection (ICSI) that leads to full term development of hybrid (B6C3F1 and B6D2F1) and inbred (C57BL/6) mouse embryos. Although fertilization and pre‐implantation development of C57BL/6 eggs were similar to those of F1 hybrid eggs, post‐implantation development of the embryos from C57BL/6 females was significantly poorer than those of the eggs from hybrid females. Reciprocal crosses of C57BL/6 and B6C3F1 gametes revealed that the low rate of post‐implantation development of C57BL/6 embryos was due to oocyte factor(s), rather than the sperm factor. Mol. Reprod. Dev. 60: 74–78, 2001. © 2001 Wiley‐Liss, Inc.

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