Premium
Taking compact NMR to monitoring real reactions in large‐scale chemical industries—General considerations and learnings from a lab‐scale test case
Author(s) -
Nestle Nikolaus,
Lim Zi Jian,
Böhringer Tobias,
Abtmeyer Sarah,
Arenz Sven,
Leinweber Felix C.,
Weiß Thomas,
Harbou Erik
Publication year - 2020
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.5061
Subject(s) - scale (ratio) , chemistry , test (biology) , focus (optics) , process engineering , engineering , physics , paleontology , quantum mechanics , optics , biology
The considerations for use of compact nuclear magnetic resonance in a large‐scale industrial environment clearly differ from those in academic and educational settings and even from those in smaller companies. In the first part of this article, these differences will be discussed along with the additional requirements that need to be fulfilled for successful applicability in different use cases. In the second part of the article, outcomes from different research activities aiming to fulfill these requirements will be presented with a focus on an online reaction‐monitoring study on a lab‐scale nucleophilic chlorination reaction.