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Sodium quantitation in soft drinks: A rapid methodology by qNMR
Author(s) -
Ravaglia Luciana Marçal,
Freitas Deisy dos Santos,
Ricci Thiago Gomes,
Nazario Carlos Eduardo Domingues,
Alcantara Glaucia Braz
Publication year - 2020
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.4950
Subject(s) - flame photometry , chemistry , sodium , analytical chemistry (journal) , sodium acetate , spectroscopy , proton nmr , nuclear magnetic resonance , chromatography , stereochemistry , organic chemistry , physics , quantum mechanics
High sodium dietary intake has a positive association with an increase in blood pressure and can be correlated with risk factors of disease. Considering that the World Health Organization recommends a sodium intake lower than 2 g day ‐1 for adults, the hidden sodium content in processed foods is an important factor that compromises the assessment of a healthy diet. Accordingly, the present paper aimed to quantitate the sodium content of conventional soft drinks and their diet versions using nuclear magnetic resonance spectroscopy as a quantitative analytical technique ( 23 Na qNMR). The results show one free sodium signal (Na + ) displayed as a singlet at 0 ppm in the 23 Na NMR spectrum, making its quantitation highly specific. This signal alone was used to directly determine the concentration of sodium in soft drinks. Flame photometry analysis was used to validate the method, and an excellent linearity was found in qNMR analysis ( r = 0.9994) in comparison with flame photometry ( r = 0.9958). In addition, a good correlation was found between sodium concentrations obtained by 23 Na NMR and flame photometry in the evaluated commercial soft drinks. Since the intensity of the resonance line is directly proportional to the number of nuclei (spins), the concentration of sodium in soft drinks can be determined via this straightforward method without the need for external calibration. The experimental acquisitions are fast (approximately 15 min), allowing the analysis of several samples in a short period of time. This is a novel alternative for sodium quantitation using an efficient NMR methodology.