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Multiplicity‐edited 1 H‐ 1 H TOCSY experiment
Author(s) -
Nolis Pau,
Parella Teodor
Publication year - 2018
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.4695
Subject(s) - homonuclear molecule , heteronuclear molecule , multiplicity (mathematics) , chemistry , coupling constant , analytical chemistry (journal) , nuclear magnetic resonance spectroscopy , stereochemistry , physics , molecule , particle physics , mathematical analysis , mathematics , organic chemistry , chromatography
A 1 H‐ 1 H total correlation spectroscopy (TOCSY) experiment incorporating 13 C multiplicity information is proposed. In addition, broadband 1 H homodecoupling in the indirect dimension can be implemented using a perfect BIRD module that affords exclusive 1 H chemical shift evolution with full decoupling of all heteronuclear and homonuclear (including 2 J HH ) coupling constants. As a complement to the normal TOCSY and the recent PSYCHE‐TOCSY experiments, this novel multiplicity‐edited TOCSY experiment distinguishes between CH/CH 3 (phased up) and CH 2 (phased down) cross‐peaks, which facilitates resonance analysis and assignment.