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Structure elucidation of new fusarielins from Fusarium sp. and their antimicrobial activity
Author(s) -
Tchoukoua Abdou,
Hasegawa Ryosuke,
Hendracipta Kurniawan Andreas,
Sato Satoru,
Koseki Takuya,
Shiono Yoshihito
Publication year - 2018
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.4662
Subject(s) - chemistry , antimicrobial , fusarium , staphylococcus aureus , stereochemistry , antibacterial activity , fungus , two dimensional nuclear magnetic resonance spectroscopy , nuclear magnetic resonance spectroscopy , bacteria , organic chemistry , botany , genetics , biology
Three new fusarielins, 3‐ epi ‐fusarielin H ( 1 ), 3‐O‐methyl‐fusarielin H ( 2 ), and 3‐O‐methyl‐ epi ‐fusarielin H ( 3 ), were isolated from the fungus Fusarium sp. together with the known analogues, fusarielins F ( 4 ) and G ( 5 ). The structures of these compounds were elucidated by analysis of their ESI‐HRTOFMS, 1D and 2D NMR spectroscopic data. The new compounds exhibited weak antibacterial effect against Staphylococcus aureus .