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Synthesis of a new 1,2,3,4,5‐pentasubstituted cyclohexanol and determining its stereochemistry by NMR spectroscopy and quantum‐chemical calculations
Author(s) -
Mamedov Ibrahim,
Abbasoglu Rza,
Bayramov Musa,
Maharramov Abel
Publication year - 2016
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.4377
Subject(s) - chemistry , cyclohexanol , conformational isomerism , cyclohexane , quantum chemical , nuclear magnetic resonance spectroscopy , computational chemistry , stereochemistry , chemical shift , spectroscopy , derivative (finance) , organic chemistry , molecule , catalysis , physics , quantum mechanics , financial economics , economics
The presence of substituents in cyclohexane can influence to the ratio of conformers; for some cases, the boat form is preferable. The new six‐membered cyclohexanol derivative 2 has been obtained by the synthesis of ( E )‐1‐(bromophenyl)‐3‐phenylpropen‐2‐one ( 1 ). The NMR and quantum‐chemical conformational analysis for the 2 have carried out, and its possible mechanism of formation was given. Copyright © 2015 John Wiley & Sons, Ltd.