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Structure elucidation of four prenylindole derivatives from Streptomyces sp. isolated from Ailuropoda melanoleuca feces
Author(s) -
Zheng Dan,
Han Li,
Jiang Yi,
Cao YanRu,
Liu Jiang,
Chen Xiu,
Li YiQing,
Huang XueShi
Publication year - 2013
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.3928
Subject(s) - chemistry , ailuropoda melanoleuca , stereochemistry , feces , indole test , microbiology and biotechnology , ecology , biology
Four new prenylindole derivatives, ( R )‐6‐(2,3‐dihydroxy‐3‐methylbutyl)indole (1), ( R )‐6‐(2,3‐dihydroxy‐3‐methylbutyl)indolin‐2‐one (2), and an unseparated mixture of ( Z )‐6‐(4‐hydroxy‐3‐methylbut‐2‐en‐1‐yl)indolin‐2‐one (3a) and ( E )‐6‐(4‐hydroxy‐3‐methylbut‐2‐en‐1‐yl)indolin‐2‐one (3b) with a ratio of 3 : 2, were isolated from the culture broth of a streptomycete isolated from Ailuropoda melanoleuca feces. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopic techniques. The absolute configuration of 1 was determined by Mosher's method. Copyright © 2013 John Wiley & Sons, Ltd.