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Structure determination of two new trichothecenes from a halotolerant fungus Myrothecium sp. GS‐17 by NMR spectroscopy
Author(s) -
Zhang SongYa,
Li ZhanLin,
Guan LiPing,
Wu Xin,
Pan HuaQi,
Bai Jiao,
Hua HuiMing
Publication year - 2012
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.3845
Subject(s) - chemistry , rhizoctonia solani , halotolerance , trichothecene , fusarium oxysporum , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , fungus , pathogenic fungus , nuclear magnetic resonance spectroscopy , fermentation , botany , toxin , organic chemistry , biochemistry , bacteria , biology , genetics , gene
Two new trichothecenes, named 8 α ‐hydroxyroridin H and myrothecin A, along with six known compounds, 8 α ‐acetoxy roridin H, isororidin K, verrucarin A, verrucarin J, verrucarin L and 8 α ‐acetoxy verrucarin L, were isolated from the fermentation broth of a halotolerant fungus Myrothecium sp. GS‐17, which was separated from the soil sample of a salina. Structure elucidation and NMR signal assignments were achieved on the basis of spectroscopy. In addition, compounds 1 and 2 were active against plant pathogenic fungi Rhizoctonia solani and Fusarium oxysporum . Copyright © 2012 John Wiley & Sons, Ltd.

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