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Steroids and an oxylipin from an algicolous isolate of Aspergillus flavus
Author(s) -
Qiao MingFeng,
Ji NaiYun,
Miao FengPing,
Yin XiuLi
Publication year - 2011
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2748
Subject(s) - oxylipin , chemistry , fusarium oxysporum , aspergillus flavus , fungus , stereochemistry , aspergillus , fusarium , botany , biochemistry , enzyme , food science , biology
A new oxylipin, (8 E ,12 Z )‐10,11‐dihydroxyoctadeca‐8,12‐dienoic acid (1), a new steroid, 3β,4α‐dihydroxy‐26‐methoxyergosta‐7,24(28)‐dien‐6‐one (2), and four known steroids, episterol (3), (22 E ,24 R )‐ergosta‐7,22‐dien‐3β,5α,6α‐triol (4), (22 E ,24 R )‐ergosta‐5,22‐dien‐3β‐ol (5), and (22 E ,24 R )‐ergosta‐4,6,8(14),22‐tetraen‐3‐one (6), were isolated from the cultures of Aspergillus flavus , an endophytic fungus isolated from the marine red alga Corallina officinalis . Their structures and relative stereochemistry were elucidated by 1D, 2D NMR and mass spectroscopic techniques. 1 and 2 exhibited low activity to inhibit acetylcholinesterase and no activity against plant pathogenic fungi Colletotrichum lagenarium and Fusarium oxysporum . Copyright © 2011 John Wiley & Sons, Ltd.