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Structure elucidation and NMR assignments of two new triterpenoids from the stems of Paragonia pyramidata (Bignoniaceae)
Author(s) -
Wang XiaoLing,
Hay AnneEmmanuelle,
Matheeussen An,
Gupta Mahabir P.,
Hostettmann Kurt
Publication year - 2011
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2726
Subject(s) - chemistry , lupeol , stigmasterol , oleanolic acid , bignoniaceae , phytochemical , two dimensional nuclear magnetic resonance spectroscopy , triterpene , stereochemistry , carbon 13 nmr , heteronuclear single quantum coherence spectroscopy , dichloromethane , triterpenoid , organic chemistry , traditional medicine , chromatography , solvent , biochemistry , medicine , alternative medicine , pathology
Phytochemical investigation of dichloromethane (DCM) extract from the stems of Paragonia pyramidata var. pyramidata L. Rich. (Bur.) resulted in the isolation and characterization of two new triterpenoids 3β,19β‐dihydroxylup‐12, 20(29)‐diene‐28‐oic acid (1) and 3β,19β‐dihydroxylup‐12‐en‐28‐oic acid (2), three known triterpenoids lupeol (3), spinosic acid A (4) and oleanolic acid (5), together with four known steroids (20R)‐22E‐24‐ethylcholesta‐4,22‐dien‐3‐one (6), (20R)‐24‐ethylcholest‐4‐en‐3‐one (7), stigmasterol (8) and β‐sitosterol (9). HREIMS, GC–MS and NMR experiments including HSQC, HMBC, COSY and NOESY were used for the determination of the structures and NMR spectral assignments. This is the first report about the chemical constituents for this plant. Copyright © 2011 John Wiley & Sons, Ltd.