Structure determination of selaginellins G and H from  Selaginella pulvinata  by NMR spectroscopy | Zendy

Cao Yuan | Zendy; Chen JiJun | Zendy; Tan NingHua | Zendy; Wu YongPing | Zendy; Yang Jie | Zendy; Wang Qiang | Zendy

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Structure determination of selaginellins G and H from Selaginella pulvinata by NMR spectroscopy

Author(s) -

Cao Yuan,

Chen JiJun,

Tan NingHua,

Wu YongPing,

Yang Jie,

Wang Qiang

Publication year - 2010

Publication title -

magnetic resonance in chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.483

H-Index - 72

eISSN - 1097-458X

pISSN - 0749-1581

DOI - 10.1002/mrc.2623

Subject(s) - chemistry , selaginella , heteronuclear single quantum coherence spectroscopy , candida albicans , nuclear magnetic resonance spectroscopy , stereochemistry , antifungal , two dimensional nuclear magnetic resonance spectroscopy , botany , microbiology and biotechnology , biology

Selaginellins G ( 1 ) and H ( 2 ), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata . Their structures were elucidated, and complete assignments of the 1 H and 13 C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC 50 value of 5.3 µg/ml. Copyright © 2010 John Wiley & Sons, Ltd.

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