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Receiver gain function: the actual NMR receiver gain
Author(s) -
Mo Huaping,
Harwood John S.,
Raftery Daniel
Publication year - 2010
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2563
Subject(s) - receiver operating characteristic , automatic gain control , gain of function , function (biology) , radio receiver design , information gain , sensitivity (control systems) , chemistry , computer science , electronic engineering , telecommunications , mathematics , statistics , engineering , artificial intelligence , bandwidth (computing) , transmitter , amplifier , biochemistry , channel (broadcasting) , evolutionary biology , biology , mutation , gene
The observed NMR signal size depends on the receiver gain parameter. We propose a receiver gain function to characterize how much the raw FID is amplified by the receiver as a function of the receiver gain setting. Although the receiver is linear for a fixed gain setting, the actual gain of the receiver may differ from what the gain setting suggests. Nevertheless, for a given receiver, we demonstrate that the receiver gain function can be calibrated. Such a calibration enables accurate comparison of separately acquired NMR signals in quantitative analysis, which frequently requires different receiver gain settings to avoid receiver saturation or achieve optimum sensitivity. The application of receiver gain function, along with the definition of receiving efficiency, allows easy concentration determination by a single internal or external concentration reference. Copyright © 2010 John Wiley & Sons, Ltd.