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Structural determination of prunusins A and B, new C‐alkylated flavonoids from Prunus domestica , by 1D and 2D NMR spectroscopy
Author(s) -
Mahmood Azhar,
Fatima Itrat,
Kosar Shaheen,
Ahmed Rehana,
Malik Abdul
Publication year - 2010
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2540
Subject(s) - chemistry , dept , nuclear magnetic resonance spectroscopy , alkylation , two dimensional nuclear magnetic resonance spectroscopy , pathogenic fungus , trichophyton , prunus , stereochemistry , spectroscopy , fungus , antifungal , botany , organic chemistry , biochemistry , microbiology and biotechnology , physics , quantum mechanics , biology , gene , catalysis
Prunusins A (1) and B (2), the new C‐alkylated flavonoids, have been isolated from the seed kernels of Prunus domestica . Their structures were assigned from 1 H and 13 C nuclear magnetic resonating spectra, DEPT and by correlation spectroscopy, HMQC and HMBC experiments. 3, 5, 7, 4′‐Tetrahydroxyflavone (3) and 3, 5, 7‐trihydroxy‐8, 4′‐dimethoxyflavone (4) have also been reported from this species. Both compounds (1) and (2) showed significant antifungal activity against pathogenic fungus Trichophyton simmi. Copyright © 2009 John Wiley & Sons, Ltd.