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1 H and 13 C NMR assignments of all three isomeric o ‐fluoronaphthaldehydes and three o ‐fluorophenanthrene aldehydes
Author(s) -
Busacca Carl A.,
Campbell Scot,
Gonnella Nina C.,
Senanayake Chris H.
Publication year - 2010
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2523
Subject(s) - chemistry , enantioselective synthesis , rhodium , catalysis , stereochemistry , proton nmr , carbon 13 nmr , medicinal chemistry , computational chemistry , organic chemistry
Three isomeric o ‐fluoronaphthaldehydes, 9‐fluorophenanthrene, and three previously unreported o ‐fluorophenanthrene aldehydes were analyzed in detail by multiple NMR techniques to provide unambiguous assignment of structures and resonances. The six aldehydes serve as the key starting materials for novel chiral ligands used in highly enantioselective rhodium‐catalyzed asymmetric hydrogenation reactions. Copyright © 2009 John Wiley & Sons, Ltd.