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Constant time gradient HSQC–iDOSY: practical aspects
Author(s) -
McLachlan A. S.,
Richards J. J.,
Bilia A. R.,
Morris G. A.
Publication year - 2009
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2518
Subject(s) - chemistry , heteronuclear single quantum coherence spectroscopy , pulse sequence , resolution (logic) , constant (computer programming) , pulse (music) , diffusion , rutin , analytical chemistry (journal) , nuclear magnetic resonance , computational chemistry , chromatography , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , thermodynamics , organic chemistry , quantum mechanics , physics , antioxidant , voltage , artificial intelligence , computer science , programming language
An improved constant time gradient HSQC–iDOSY pulse sequence is presented, and the corresponding form of the Stejskal–Tanner equation is derived. The pulse sequence is particularly well suited to the problem of analysing mixtures of chemically cognate species, where the high spectral resolution afforded by 1 H 13 C correlation methods is needed for DOSY experiments to give good diffusion resolution. Its use is illustrated for a mixture of rutin and its aglycone quercetin. Copyright © 2009 John Wiley & Sons, Ltd.