Premium
Structure determination of chamaedryosides A—C, three novel nor‐ neo ‐clerodane glucosides from Teucrium chamaedrys , by NMR spectroscopy
Author(s) -
Fiorentino Antonio,
D'Abrosca Brigida,
Ricci Andreina,
Pacifico Severina,
Piccolella Simona,
Monaco Pietro
Publication year - 2009
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2499
Subject(s) - teucrium , chemistry , heteronuclear single quantum coherence spectroscopy , dept , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , carbon 13 nmr , traditional medicine , lamiaceae , medicine
Three new nor‐ neo ‐clerodane diterpenes, named chamaedryoside A (1), B (2) and C (3), have been isolated from the organic extracts of Teucrium chamaedrys (L.) and their structural characterization has been accomplished by 1 H and 13 C‐NMR spectra, and DEPT, by COSY, TOCSY, HSQC, HSQC‐TOSCY and HMBC experiments, as well as by ESI‐MS/MS techniques. The stereostructures have been elucidated by NOESY and computational calculations. Copyright © 2009 John Wiley & Sons, Ltd.