Premium
Derivatives of pyrazinecarboxylic acid: 1 H, 13 C and 15 N NMR spectroscopic investigations
Author(s) -
Holzer Wolfgang,
Eller Gernot A.,
Datterl Barbara,
Habicht Daniela
Publication year - 2009
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2437
Subject(s) - chemistry , coupling constant , tautomer , chemical shift , nmr spectra database , carbon 13 nmr satellite , nuclear magnetic resonance spectroscopy , spectral line , analytical chemistry (journal) , stereochemistry , crystallography , computational chemistry , fluorine 19 nmr , organic chemistry , physics , particle physics , astronomy
NMR spectroscopic studies are undertaken with derivatives of 2‐pyrazinecarboxylic acid. Complete and unambiguous assignment of chemical shifts ( 1 H, 13 C, 15 N) and coupling constants ( 1 H, 1 H; 13 C, 1 H; 15 N, 1 H) is achieved by combined application of various 1D and 2D NMR spectroscopic techniques. Unequivocal mapping of 13 C, 1 H spin coupling constants is accomplished by 2D (δ, J ) long‐range INEPT spectra with selective excitation. Phenomena such as the tautomerism of 3‐hydroxy‐2‐pyrazinecarboxylic acid are discussed. Copyright © 2009 John Wiley & Sons, Ltd.