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1 H and 13 C NMR assignments for new heterocyclic TAM leuco dyes, (2 Z ,2′ E )‐2,2′‐(2‐phenyl propane‐1,3‐diylidene) bis(1,3,3‐trimethylindoline) derivatives. Part II
Author(s) -
Keum SamRok,
Roh SeJung,
Lee MinHyung,
Sauriol Francoise,
Buncel Erwin
Publication year - 2008
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2255
Subject(s) - chemistry , dept , malachite green , two dimensional nuclear magnetic resonance spectroscopy , proton nmr , heteronuclear single quantum coherence spectroscopy , propane , nmr spectra database , carbon 13 nmr , stereochemistry , nuclear magnetic resonance spectroscopy , medicinal chemistry , spectral line , organic chemistry , physics , adsorption , astronomy
The 1 H and 13 C NMR spectra of the novel heterocyclic Leuco‐TAM dyes, (2 Z , 2′ E )‐2,2′‐(2‐phenyl propane‐1,3‐diylidene) bis(1,3,3‐trimethylindoline) derivatives 1–4 as precursors of triarylmethane (TAM) + (Malachite Green FB‐analog) dyes were completely assigned by 1D and 2D NMR experiments, including DEPT, COSY, HSQC, HMBC, and NOESY. Especially, the diastereotopic gem ‐dimethyl protons at the C3 and C3′ positions of the FB rings were definitively assigned. The ( Z , E ) isomers adopt the energetically favored three‐bladed propeller conformation in solution. Copyright © 2008 John Wiley & Sons, Ltd.