Microbial transformation of the diterpene mulin‐11,13‐dien‐20‐oic acid by   Mucor plumbeus | Zendy

Areche Carlos | Zendy; Loyola Luis A. | Zendy; Borquez Jorge | Zendy; Rovirosa Juana | Zendy; SanMartin Aurelio | Zendy

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Microbial transformation of the diterpene mulin‐11,13‐dien‐20‐oic acid by Mucor plumbeus

Author(s) -

Areche Carlos,

Loyola Luis A.,

Borquez Jorge,

Rovirosa Juana,

SanMartin Aurelio

Publication year - 2008

Publication title -

magnetic resonance in chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.483

H-Index - 72

eISSN - 1097-458X

pISSN - 0749-1581

DOI - 10.1002/mrc.2238

Subject(s) - chemistry , diterpene , stereochemistry , transformation (genetics) , biochemistry , gene

Two new mulinane‐type derivatives: 16‐hydroxy mulin‐11,13‐dien‐20‐oic (2) acid and 7α,16‐dihydroxy mulin‐11,13‐dien‐20‐oic (3) acid were obtained by microbial transformation of mulin‐11,13‐dien‐20‐oic acid (1), along with tyrosol (4) using liquid cultures of Mucor plumbeus . The latter compound has not been previously identified in the genus Mucor . Structural elucidation of these metabolites was achieved using 1D‐ and 2D‐NMR spectroscopy. Copyright © 2008 John Wiley & Sons, Ltd.

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