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Complete assignments of 1 H and 13 C NMR spectral data for three polyhydroxylated 12‐ursen‐type triterpenoids from Dischidia esquirolii
Author(s) -
Ma Xiaoxia,
Yang Chongren,
Zhang Yingjun
Publication year - 2008
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2212
Subject(s) - chemistry , epimer , stereochemistry , triterpenoid , ursolic acid , nmr spectra database , nuclear magnetic resonance spectroscopy , spectral line , chromatography , astronomy , physics
Abstract The complete assignments of all the 1 H and 13 C NMR signals of three polyhydroxylated 12‐ursen‐type triterpenes, 6β,19α,22α‐trihydroxyurs‐12‐en‐3‐oxo‐28‐oic acid (1), 3β,6α,19α,23‐tetrahydroxyurs‐12‐en‐28‐ oic acid (2) and 3β,6β,19α,23‐tetrahydroxyurs‐12‐en‐28‐oic acid (3), were carried out by means of homo‐ and hetero‐nuclear two‐dimensional NMR experiments. Compounds 1–3 were isolated from the aerial parts of Dischidia esquirolii . Of them, 1 and 2 were identified as new polyhydroxylated ursolic acid derivatives. Compound 2 is the C‐6 hydroxyl epimer of 3, which was isolated first from Adina rubella , and its structure is revised in this paper. Copyright © 2008 John Wiley & Sons, Ltd.