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New furostanol saponins from Allium ascalonicum L.
Author(s) -
Kang LiPing,
Liu ZhiJun,
Zhang Lei,
Tan DaWei,
Zhao Yang,
Zhao Yu,
Chen HeBing,
Ma BaiPing
Publication year - 2007
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.2037
Subject(s) - chemistry , stereochemistry , saponin , allium , two dimensional nuclear magnetic resonance spectroscopy , liliaceae , botany , medicine , alternative medicine , pathology , biology
Abstract An analysis of the polar extracts from Allium ascalonicum L. led to the isolation of two new furostanol saponins (compound 1 and 2) and two known furostanol saponins (compound 3 and 4). On the basis of 1D and 2D NMR (including 1 H, 13 C NMR, 1 H 1 H COSY, HSQC, TOCSY, HMBC, and NOESY), FAB‐MS spectrometry, and chemical methods, their structures were elucidated as (25 R )‐26‐ O ‐β‐ D ‐glucopyranosyl‐22‐hydroxy‐5α‐furost‐2‐one‐3β, 5, 6β, 26‐tetraol‐3‐ O ‐α‐ L ‐rhamnopyranosyl‐(1→2)‐β‐ D ‐glucopyranoside (ascalonicoside C, 1), (25 R )‐26‐ O ‐β‐ D ‐glucopyranosyl‐22‐methoxy‐5α‐furost‐2‐one‐3β, 5, 6β, 26‐tetraol‐ 3‐ O ‐α‐ L ‐rhamnopyranosyl‐(1→2)‐β‐ D ‐glucopyranoside (ascalonicoside D, 2), (25 R )‐26‐ O ‐β‐ D ‐glucopyranosyl‐22‐hydroxy‐5‐ene‐furostan‐3β, 26‐diol‐3‐ O ‐α‐ L ‐rhamnopyranosyl‐(1→4)‐α‐ L ‐rhamnopyranosyl‐(1→4)‐[α‐ L ‐rhamnopyranosyl‐(1→2)]‐β‐ D ‐glucopyranoside (dichotomin, 3), and (25 R )‐26‐ O ‐β‐ D ‐glucopyranosyl‐22‐hydroxy‐5‐ene‐furostan‐3β, 26‐diol‐3‐ O ‐α‐ L ‐rhamnopyranosyl‐(1→2)‐[α‐ L ‐arabinofuranosyl‐(1→4)]‐β‐ D ‐ glucopyranoside (parisaponin I, 4). Copyright © 2007 John Wiley & Sons, Ltd.