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Unambiguous NMR spectral assignments of salvinorin A
Author(s) -
Giner JoséLuis,
Kiemle David J.,
Kutrzeba Lukasz,
Zjawiony Jordan
Publication year - 2007
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1972
Subject(s) - chemistry , heteronuclear single quantum coherence spectroscopy , hallucinogen , two dimensional nuclear magnetic resonance spectroscopy , carbon 13 nmr , stereochemistry , proton nmr , psychology , psychiatry
The complete assignments of the 1 H and 13 C NMR spectra of the hallucinogenic neoclerodane diterpenoid salvinorin A were determined in three different NMR solvents using HSQC, HMBC and COSY. Solvent systems are described that allow the resolution of all 1 H signals. Virtual coupling was observed for the protons at C‐2, C‐3 and C‐4 in the 600 MHz 1 H spectrum in CDCl 3 . The complete assignments of the 1 H and 13 C NMR spectra of salvinorin B are also reported. Copyright © 2007 John Wiley & Sons, Ltd.