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Selective excitation of overlapping multiplets; the application of doubly selective and chemical shift filter experiments to complex NMR spectra
Author(s) -
Duncan Sara J.,
Lewis Richard,
Bernstein Michael A.,
Sandor Peter
Publication year - 2007
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1962
Subject(s) - chemistry , excitation , chemical shift , filter (signal processing) , spectral line , quantum chemical , analytical chemistry (journal) , computational chemistry , molecule , organic chemistry , quantum mechanics , physics , computer science , computer vision
Standard 1D TOCSY and NOE experiments have limitations where signals are severely overlapped. Here, two recently published selective excitation methods are evaluated, the first of which uses a chemical shift selective filter to select a single resonance based on its chemical shift, and the second of which is a doubly selective experiment comprising a 1D TOCSY preparation step and subsequent 1D NOE. We also demonstrate the improvement in spectral quality obtained by the use of the zero quantum filter, which is incorporated into both of these experiments. The application of these different methods of selectively exciting overlapped multiplets, to different types of samples is considered. Copyright © 2007 John Wiley & Sons, Ltd.