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Isolation and structural determination of sorbinols A and B, new triterpenes from Sorbus cashmariana , by 1D and 2D NMR spectroscopy
Author(s) -
Kazmi Mehdi Hassan,
Ahmed Ejaz,
Hameed Saira,
Malik Abdul,
Ashraf Muhammad
Publication year - 2007
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1961
Subject(s) - chemistry , terpene , dept , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , nuclear magnetic resonance spectroscopy , ethyl acetate , organic chemistry
Two new pentacyclic triterpenes, sorbinols A (1) and B (2) have been isolated from the ethyl acetate fraction of Sorbus cashmariana and their structures assigned from 1 H and 13 C NMR spectra, DEPT and by 2D COSY, NOE, HMQC and HMBC experiments. Both 1 and 2 showed moderate inhibitory potential against the enzyme lipoxygenase. Copyright © 2007 John Wiley & Sons, Ltd.