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13 C NMR spectroscopy of some third‐generation cephalosporins, their synthetic intermediaries and reaction byproducts
Author(s) -
López Miguel A.,
Rodríguez Zalua,
González Maritza,
Tolón Blanca,
Avila Rizette,
Rodríguez Juan C.,
VélezCastro Hermán,
Fini Adamo
Publication year - 2007
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1952
Subject(s) - chemistry , cephem , cephalosporin , nuclear magnetic resonance spectroscopy , chemical shift , carbon 13 nmr , fluorine 19 nmr , stereochemistry , cephalosporin antibiotic , organic chemistry , carboxylic acid , antibiotics , biochemistry
13 C NMR spectroscopic data for 25 cephalosporin derivatives were assigned by combination of one‐ and two‐dimensional experiments. The effect of the substitution at C‐3, C‐7 and C‐4 acid group positions on the chemical shifts of the cephem nucleus is discussed. Copyright © 2007 John Wiley & Sons, Ltd.