Premium
Solution NMR of membrane proteins: practice and challenges
Author(s) -
Sanders Charles R.,
Sönnichsen Frank
Publication year - 2006
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1816
Subject(s) - chemistry , lipid bilayer , integral membrane protein , membrane protein , membrane , bilayer , biochemistry
This review focuses upon the application of solution NMR methods to multispan integral membrane proteins, particularly with respect to determination of global folds by this approach. Practical methods are described along with the special difficulties that confront the application of solution NMR to proteins that dwell in the netherworld of the lipid bilayer. Copyright © 2006 John Wiley & Sons, Ltd.