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Synthesis and total assignment of 1 H and 13 C NMR spectra of new oxoisoaporphines by long‐range heteronuclear correlations
Author(s) -
SobarzoSánchez Eduardo,
De la Fuente Julio,
Castedo Luis
Publication year - 2005
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1703
Subject(s) - chemistry , heteronuclear molecule , acetic acid , nmr spectra database , sulfuric acid , carbon 13 nmr , proton nmr , spectral line , medicinal chemistry , nuclear magnetic resonance spectroscopy , stereochemistry , organic chemistry , physics , astronomy
The new oxoisoaporphines 7 H ‐dibenzo[ de,h ]quinolin‐7‐one, 5‐methoxy‐7 H ‐dibenzo[ de,h ]quinolin‐7‐one, 5‐methoxy‐6‐hydroxy‐7 H ‐dibenzo[ de,h ]quinolin‐7‐one, 5‐hydroxy‐7 H ‐dibenzo[ de,h ]quinolin‐7‐one and 5‐methoxy‐6 H ‐dibenzo[ de,h ]quinolin‐6‐one were prepared either by oxidation of their 2,3‐dihydro derivatives or by heating (2′‐(3,4‐dihydro‐6,7‐dimethoxyisoquinolin‐1′‐yl)phenyl)methylbenzoate with an acetic acid/sulfuric acid mixture at 100 °C. The structures were confirmed and 1 H and 13 C NMR spectra were completely assigned using two‐dimensional NMR techniques. Copyright © 2005 John Wiley & Sons, Ltd.