Premium
1 H and 13 C NMR spectral assignment of androstane derivatives
Author(s) -
Fuente Ariadna,
Reyes Mayra,
Alvarez Yoanna M.,
Ruiz José A.,
Vélez Hermán,
ViñasBravo Omar,
MontielSmith Sara,
MezaReyes Socorro,
SandovalRamírez Jesús
Publication year - 2005
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1605
Subject(s) - chemistry , substituent , androsterone , chemical shift , androstane , stereochemistry , coupling constant , carbon 13 nmr , proton nmr , computational chemistry , steroid , biochemistry , physics , particle physics , hormone
1 H and 13 C NMR spectroscopic data for 5α‐androstanes and halo‐5α‐androstanes with different substituents at positions C‐3, C‐9, C‐11 and C‐17 were examined and assigned by a combination of 1D and 2D NMR experiments. The substituent effects on the 13 C chemical shifts were compared with those of epi ‐androsterone, used as a reference compound. The coupling constants n J ( 19 F, 13 C) were measured for compounds 6, 8, 11 and 14. Copyright © 2005 John Wiley & Sons, Ltd.