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Application of residual dipolar couplings in organic compounds
Author(s) -
Yan Jiangli,
Zartler Edward R.
Publication year - 2005
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1505
Subject(s) - chemistry , residual dipolar coupling , biomolecule , residual , organic molecules , dipole , anisotropy , nuclear magnetic resonance spectroscopy , molecule , computational chemistry , spectroscopy , chemical physics , stereochemistry , organic chemistry , optics , biochemistry , physics , algorithm , computer science , quantum mechanics
Residual dipolar couplings (RDCs) induced by anisotropic media are a powerful tool for the structure determination of biomolecules through NMR spectroscopy. Recent advances have proven it to be a valuable tool for determination of the stereochemistry of organic molecules. By simple inspection or order matrix calculations, RDCs provide unambiguous information about the relative configurations or complete stereochemistry of organic compounds. Copyright © 2004 John Wiley & Sons, Ltd.