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Additive of substituent effects on the chemical shift of the formyl proton in disubstituted benzaldehydes
Author(s) -
Castañeda H. O.,
Contreras R. H.,
de Kowalewski D. G.
Publication year - 1980
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270130421
Subject(s) - substituent , nitromethane , additive function , chemistry , proton , chemical shift , dilution , computational chemistry , medicinal chemistry , organic chemistry , mathematics , physics , thermodynamics , mathematical analysis , quantum mechanics
An additivity relationship of substituent effects on the formyl proton chemical shift has been tested with ten disubstituted benzaldehydes. In most cases it is found that the formyl proton chemical shift, extrapolated to infinite dilution in nitromethane, is in good agreement with that calculated using the additivity relationship.