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Quantitative analysis of a mixture of cresols by carbon‐13 NMR spectroscopy
Author(s) -
Chiang HungCheh,
Lin LongJin
Publication year - 1979
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270120419
Subject(s) - cresol , chemistry , methanol , analytical chemistry (journal) , toluidine , calibration curve , spectroscopy , carbon 13 nmr , nuclear magnetic resonance spectroscopy , chromatography , organic chemistry , detection limit , phenol , physics , quantum mechanics
The suitability of 13 C NMR as a technique for determining o ‐, m , and p ‐cresols in their mixtures was investigated. Spectra were determined in methanol, containing o ‐toluidine as an internal standard, without nuclear Overhauser suppression. Ratios of peak areas of each cresol isomer to o ‐toluidine were determined by means of the standard calibration method, and then mixtures of cresol isomers were prepared and quantified in varying concentrations from 8.30 to 66.84 mol% for each isomer, with an average absolute error of 0.78% for all isomers. The method described was convenient and the results were generally satisfactory.