Premium
NMR study of catechol and some catecholamines
Author(s) -
Lambert Françoise,
Ellenberger Michel,
Merlin Louis,
Cohen Yves
Publication year - 1975
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270070605
Subject(s) - catechol , chemistry , chemical shift , tyramine , proton magnetic resonance , additive function , substituent , coupling constant , amphetamine , computational chemistry , dopamine , proton , nuclear magnetic resonance , stereochemistry , organic chemistry , physics , biochemistry , psychology , neuroscience , mathematics , particle physics , quantum mechanics , mathematical analysis
The proton magnetic resonance spectra of catechol, epinephrine, dopamine, synephrine, tyramine and amphetamine have been analysed by computer simulation. The chemical shifts and coupling constants are discussed, with their molecular implications. Convenient parameters are introduced for the additivity of substituent effects on chemical shifts of aromatic protons. The additivity rule of coupling constants is extended to these compounds.