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Chemical shift non‐equivalence of methylene protons adjacent to an asymmetric nitrogen atom
Author(s) -
Vigevani A.,
Gioia B.,
Cavalleri B.,
Gallo G. G.
Publication year - 1971
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270030210
Subject(s) - geminal , methylene , vicinal , steric effects , nitrogen atom , chemistry , nitrogen , coupling constant , chemical shift , computational chemistry , equivalence (formal languages) , crystallography , stereochemistry , medicinal chemistry , organic chemistry , physics , mathematics , quantum mechanics , group (periodic table) , pure mathematics
The chemical shift non‐equivalence of the methylene protons adjacent to the quaternary nitrogen in compounds of the type has been investigated. The behaviour of the examined compounds is interpreted in terms of different rotation rates around the three CN ⊕ bonds. The vicinal and geminal coupling constants of the non‐equivalent methylene protons are also reported and discussed in terms of steric factors.