Premium
Chemical shift non‐equivalence of ring protons in N‐substituted β‐lactams
Author(s) -
Vigevani A.,
Gioia B.,
Gallo G. G.
Publication year - 1970
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270020311
Subject(s) - equivalence (formal languages) , nitrogen atom , ring (chemistry) , carbon atom , nitrogen , atom (system on chip) , chemistry , stereochemistry , crystallography , mathematics , pure mathematics , organic chemistry , computer science , embedded system
A study is reported on the chemical shift non‐equivalence of the diastereotopic protons at C‐4 in identically 3,3‐disubstituted β‐lactams having an asymmetric carbon atom in positions ranging from β to ε of the chain attached to the nitrogen atom. The non‐equivalence has been correlated with the nature of the substituents bonded to the chiral centre and to its distance from the C‐4 protons.