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The NMR spectra of some 3‐coordinate phosphorus compounds containing chloromethyl and isopropyl groups
Author(s) -
Bissey J. E.,
Goldwhite H.,
Rowsell D. G.
Publication year - 1970
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/mrc.1270020202
Subject(s) - isopropyl , chemistry , nmr spectra database , fluoride , coupling constant , chloride , ion , spectral line , phosphorus , phosphorus 31 nmr spectroscopy , crystallography , inorganic chemistry , nuclear magnetic resonance spectroscopy , medicinal chemistry , stereochemistry , organic chemistry , physics , particle physics , astronomy
Analysis of the proton NMR spectra of Pr 1 PCINMe 2 indicates magnetic non‐equivalence of the methyl groups due to the adjacent asymmetric phosphorus atom. High temperatures, or the addition of chloride ion, induce an exchange reaction with inversion of configuration at phosphorus. The corresponding fluoride is configurationally stable at high temperatures. The compounds CICH 2 PXNR 2 (X = Cl, F; R = Me, Et) have non‐equivalent protons in the chloromethyl group. The two HCP coupling constants in the chlorides of this series are of opposite sign, whereas in the fluorides they are of the same sign.