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29 Si and 13 C NMR spectra of tert ‐butyldimethylsilyl derivatives of amino acids
Author(s) -
Kubec Roman,
Velíšek Jan,
Kvíčalová Magdalena,
Čermák Jan,
Schraml Jan
Publication year - 1995
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260330609
Subject(s) - chemistry , chemical shift , trimethylsilyl , nmr spectra database , spectral line , stereochemistry , amino acid , nuclear magnetic resonance spectroscopy , medicinal chemistry , biochemistry , physics , astronomy
29 Si and 13 C NMR chemical shifts are reported for tert ‐butyldimethylsilyl (TBDMS) derivatives of ten common amino acids. The 29 Si chemical shifts of TBDMS derivatives of various functionalities encountered fall into distinct spectral regions. The 29 Si chemical shifts correlate linearly ( r = 0.999) with the 29 Si shifts reported earlier for the trimethylsilyl (TMS) derivatives of the same amino acids, the 29 Si chemical shift values in the TBDMS derivatives being larger than those in the TMS derivatives (in SiN groups this downfiled shift varies between 3.8 and 5.8 ppm and in SiO groups between 1.4 and 1.7 ppm).