Premium
Total assignment of the 1 H and 13 C NMR chemical shifts of four bufadienolides by 2D NMR spectroscopy
Author(s) -
Reynolds William F.,
Maxwell Anderson,
Telang Balchandur,
Bedaisie Kishore,
Ramcharan Gangadeen
Publication year - 1995
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260330515
Subject(s) - chemistry , bufalin , dept , two dimensional nuclear magnetic resonance spectroscopy , nuclear magnetic resonance spectroscopy , fluorine 19 nmr , nmr spectra database , carbon 13 nmr , chemical shift , carbon 13 nmr satellite , heteronuclear single quantum coherence spectroscopy , proton nmr , stereochemistry , spectral line , apoptosis , biochemistry , physics , astronomy
Four known bufadienolides, marinobufagin (1), telocinobufagin (2), bufalin (3) and resibufogenin (4), were isolated from the toad Bufo marinus. The 1 H and 13 C NMR spectra were completely assigned by using a combination of 13 C DEPT and 2D NMR experiments ( 1 H 1 H COSY, HMQC, HMBC and NOESY). The full 1 H NMR data for 1–4 and 1 H and 13 C NMR data for 2 are reported for the first time.