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Spectral separation of two very closely related organic compounds by 1D TOCSY
Author(s) -
Kanthimathi T.,
Moorthy Y. V. S. Narayana,
Pillai C. N.,
Subramanian S.
Publication year - 1994
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260320804
Subject(s) - chemistry , lithium aluminium hydride , analytical chemistry (journal) , phase (matter) , lithium (medication) , filtration (mathematics) , nuclear magnetic resonance spectroscopy , spectroscopy , chromatography , stereochemistry , organic chemistry , medicine , statistics , physics , mathematics , quantum mechanics , endocrinology
The use of one‐dimensional total correlation spectroscopy (1D TOCSY) combined with the z‐filtration technique to generate pure phase subspectra of individual isomers from the spectrum of the corresponding mixture without any chemical separation of the mixture is described. A straightforward spectral assignment is achieved for the isomers obtained on lithium aluminium hydride reduction of 2,7‐dioxatetracyclo[3.3.0 4,9 .0 8,11 ] undeca‐3,6‐dione (dilactone) by studying the subspectrum of each isomer as a function of the propagation time of magnetization through the network of coupled protons.