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Multinuclear NMR study of protonation in some indolizine systems
Author(s) -
Wiench Jerzy W.,
Stefaniak Lech,
Webb Graham A.
Publication year - 1994
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260320613
Subject(s) - chemistry , protonation , trifluoroacetic acid , indolizine , carbon 13 nmr , medicinal chemistry , nuclear magnetic resonance spectroscopy , stereochemistry , organic chemistry , ion
Abstract 1 H, 13 C and 15 N NMR data are presented for seven indolizine derivatives in solutions of dimethyl sulphoxide and trifluoroacetic acid (TFA). The TFA solutions contain species protonated at position N‐1 in all cases. The most definitive evidence for the site of protonation is provided by the 15 N results.