Deuterium isotope effects as evidence for substituent perturbation of the π‐electron frame in benzanilides | Zendy

MoralesRíos Martha S. | Zendy; PérezAlvarez Víctor | Zendy; JosephNathan Pedro | Zendy; Zepeda L. Gerardo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Deuterium isotope effects as evidence for substituent perturbation of the π‐electron frame in benzanilides

Author(s) -

MoralesRíos Martha S.,

PérezAlvarez Víctor,

JosephNathan Pedro,

Zepeda L. Gerardo

Publication year - 1994

Publication title -

magnetic resonance in chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.483

H-Index - 72

eISSN - 1097-458X

pISSN - 0749-1581

DOI - 10.1002/mrc.1260320506

Subject(s) - chemistry , deuterium , kinetic isotope effect , isotope , substituent , nitrogen , nitrogen atom , conjugated system , computational chemistry , crystallography , medicinal chemistry , atomic physics , organic chemistry , nuclear physics , physics , polymer , group (periodic table)

Deuterium isotope effects on 13 C nuclear shielding, n ΔC(D), transmitted across a D‐labelled nitrogen atom were investigated for a series of para ‐substituted benzanilides. The two two‐bond isotope shifts, 2 ΔC(D) are perturbed essentially in a trough‐bond manner by change of the contribution of mesomeric structures. The magnitudes of 2 Δ(CO) and 2 Δ(C‐1′) are found to be mutually interdependent as evidenced by the linear relationships between the average values of 2 Δ(CO) and 2 Δ(C‐1′) with 1 H(NH) chemical shifts and with 15 N SCS. This behaviour is interpreted as resulting from a cross‐conjugated transmission pathway involving the carbons sharing the D‐labelled nitrogen.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research