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Solasodine and diosgenin: 1 H and 13 C assignments by two‐dimensional NMR spectroscopy
Author(s) -
Puri Raman,
Wong Tuck C.,
Puri Ravi K.
Publication year - 1993
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260310313
Subject(s) - chemistry , solasodine , diosgenin , nuclear magnetic resonance spectroscopy , stereochemistry , organic chemistry , botany , solanum , biology
Solasodine and diosgenin have been widely used as starting materials for the partial synthesis of cortisone, progresterone and C21 steroidal derivatives (oral contraceptives). This study involved the total 1 H and 13 C spectral assignments of these two important compounds by using two‐dimensional NMR techniques (COSY, CSCM and HMBC), and resulted in unambiguous spectral assignments, especially in the convoluted regions of the spectra ( 1 H, 0.7–2.0 ppm; 13 C, 28–35 ppm).