Structural studies on clarithromycin (6‐ O ‐methylerythromycin A): Assignments of the  1 H and  13 C NMR spectra in organic and aqueous solutions | Zendy

Awan Abida | Zendy; Barber Jill | Zendy; Brennan Richard J. | Zendy; Parkinson John A. | Zendy

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Structural studies on clarithromycin (6‐ O ‐methylerythromycin A): Assignments of the 1 H and 13 C NMR spectra in organic and aqueous solutions

Author(s) -

Awan Abida,

Barber Jill,

Brennan Richard J.,

Parkinson John A.

Publication year - 1992

Publication title -

magnetic resonance in chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.483

H-Index - 72

eISSN - 1097-458X

pISSN - 0749-1581

DOI - 10.1002/mrc.1260301213

Subject(s) - chemistry , clarithromycin , aqueous solution , ketone , nmr spectra database , spectral line , erythromycin , nuclear magnetic resonance spectroscopy , medicinal chemistry , stereochemistry , organic chemistry , antibiotics , biochemistry , physics , astronomy

Full assignments of the 1 H and 13 C NMR spectra of clarithromycin (6‐ O ‐methylerythromycin A) in CDCl 3 and buffered D 2 O were carried out. In contrast to erythromycin A, clarithromycin exists as a single isomer, the 9‐ketone, in aqueous solution.

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