Premium
1 H and 13 C NMR studies of substituted isoquinolinium derivatives in different solvents
Author(s) -
Werra W.,
Heber D.,
Holzgrabe U.
Publication year - 1992
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260300712
Subject(s) - chemistry , isoquinoline , substituent , reactivity (psychology) , nucleophile , chemical shift , reagent , medicinal chemistry , nitro , carbon 13 nmr , organic chemistry , catalysis , medicine , alkyl , alternative medicine , pathology
1 H and 13 C NMR data for 1‐cyano‐, 4‐cyano‐, 4‐bromo‐ and 4‐bromo‐5‐nitro‐substituted isoquinolines, isoquinoline N‐oxides and N‐methoxy and N‐ethyl salts in different solvents are reported. The substituent chemical shifts are discussed with regard to the reactivity of the N‐methoxy compounds in the presence of nucleophilic reagents.