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Detection of long‐range couplings in oligomers and evaluation of coupling constants in polymers. Application of the 1D COSY technique
Author(s) -
Uhrínová Stanislava,
Uhrín Dušan,
Liptaj Tibor,
Batta Gy.
Publication year - 1991
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260290106
Subject(s) - chemistry , coupling constant , macromolecule , proton , coupling (piping) , relaxation (psychology) , range (aeronautics) , polymer , polarization (electrochemistry) , computational chemistry , analytical chemistry (journal) , chromatography , nuclear physics , organic chemistry , physics , quantum mechanics , psychology , social psychology , biochemistry , materials science , composite material , mechanical engineering , engineering
One‐dimensional COSY is shown to be a promising technique for the detection of small, unresolved proton‐proton coupling constants. Under certain circumstances the method can be more effective than two‐dimensional phase‐sensitive COSY. A detailed analysis of the experimental conditions is presented. The possible application of the method in oligosaccharide sequencing is outlined. Another potential use of one‐dimensional COSY is in the evaluation of coupling constants in macromolecules. In this case the efficiency of the polarization transfer is decreased owing to the fast transverse relaxation times of the protons. DISCO analysis was applied for the determination of coupling constants in unresolved multiplets.